Abstract:
The lower respiratory tract infections (LRTI) are the most frequent respiratory diseases among HIV infected patients and are frequently the first clinical manifestations of the HIV infections. The overall rate of bacterial pneumonia in HIV infected persons is approximately six times greater than in general population. The aim of the present study is to determine the profile of bacteria and antibiotic susceptibility pattern in sputum of HIV positive patients with Lower Respiratory Tract Infections in this region. This is a prospective study. One hundred HIV seropositive and fifty HIV non-reactive patients, of both sexes, having LRTI (clinical and radiological), were included. An early morning expectorated sputum sample from patients enrolled was collected, aerobic culture was done and antibiotic susceptibility testing was done by Kirby Bauer disc diffusion method as per CLSI guidelines. 29strains of pathogenic bacteria were isolated from HIV positives and 9 strains from HIV negatives. Amongst them the most common was Staphylococcus aureus (62 %) followed by Klebsiella pneumoniae (17.24%), Pseudomonas aeruginosa (13.79%) and Escherichia coli (6.6%) in HIV positive patients. The percentage of multiple resistances of isolates to antibiotics tested from HIV/AIDS was found to be higher than that of HIV negative patients. In conclusion the lower respiratory illness is significantly higher in HIV positive cases than the HIV seronegative cases. Emergence of multidrug resistant bacteria are threat for the patient with HIV.
Biography:
Dr Sonal is a Medical Microbiologist from India. She is a medical graduate and postgraduate in Medical. Microbiolgy from S N Medical College Jodhpur, Rajasthan. She had worked as a resident doctor in prime institutions like VMMC and SAFDARJUNG HOSPITAL New Delhi and GIPMER, New Delhi. She has the experience of working in the field of Medical Microbiology and Hospital Infection Control in renowned institutions like PGIMS, Rohtak, VMMC and Safdarjung Hospital, Govind Ballabh Pant Institute of Medical Education and Research and National Centre for Disease Control (NCDC), Delhi and in private sector as well. She has published over 15 research papers in various national and international journals. She has the experience of teaching MBBS, MD Microbiology, BDS. and Medical Laboratory Technology students She has been Trained for Internal auditor of NABL as per 15189:2012 guidelines. She has also taken part as the Incharge of National Programme like IBBS for HIV.
